Before modern refrigerators, Russian and Finnish people would keep live brown frogs in their milk to keep it fresh. It was found that the secretions made by the frogs basically act as antibiotics, killing bacteria, and keeping the milk fresh and safe to drink.
A local folk remedy in Boho, Ireland was to place soil from the local church under a pillow while you slept to cure infections. In 2018 a microbiologist found the churchyard’s soil contains a previously unknown strain of streptomyces which can be used to create antibiotics.
Alexander Fleming discovered penicillin, but never tried to make an antibiotic out of it. It was not until a decade later that a man named Howard Florey found Fleming’s little-known paper and realized the mold’s potential. Florey’s work is estimated to have saved up to 200,000,000 lives.
It was a lucky chance that we tested penicillin on mice instead of guinea pigs, because penicillin is toxic to guinea pigs and thus penicillin would have been discarded. This possibly would have never made us realize the field of antibiotics.
80% of all antibiotics produced in the U.S. are given to farm animals.
People in the U.S. without insurance will sometimes buy antibiotics for fish as they are the same grade and dosage as human antibiotics but do not require a prescription.