Lisa Kudrow (Phoebe from the sitcom Friends) published an academic paper in neurology the same year that Friends debuted on TV.
Candid Camera host Allen Funt was once on a flight that was hijacked and flown to Cuba. Because everyone on the plane recognized him they thought it was part of a stunt and did not realise the danger they were in and started enjoying themselves and gave the hijacker a standing ovation.
Hitler comedy “Heil Honey, I’m Home!” was a British sitcom featuring Adolf Hitler, Eva Braun and the Jewish couple next door. It was canceled after one episode.
The 1992 comedy “My Cousin Vinny” is so well regarded in the US legal community that it is frequently used in law schools to demonstrate courtroom procedures such as voire dire and cross examination.